Rutin ameliorates cyclophosphamide-induced reproductive toxicity in male rats
نویسندگان
چکیده
منابع مشابه
decapeptyl ameliorates cyclophosphamide-induced reproductive toxicity in male balb/c mice: histomorphometric, stereologic and hormonal evidences
background: gonadotropin-releasing hormone (gnrh) is a reproductive key hormone. the gnrh analogues are widely used in in vitro fertilization and treatment of sex hormone-depended cancers induced by the materials used in chemotherapeutic agents. objective: the aim of this study is to evaluate the effects of cyclophosphamide and decapeptyl (analogues of gnrh) on histomorphometry and stereology o...
متن کاملDecapeptyl ameliorates cyclophosphamide-induced reproductive toxicity in male Balb/C mice: histomorphometric, stereologic and hormonal evidences
BACKGROUND Gonadotropin-releasing hormone (GnRH) is a reproductive key hormone. The GnRH analogues are widely used in in vitro fertilization and treatment of sex hormone-depended cancers induced by the materials used in chemotherapeutic agents. OBJECTIVE The aim of this study is to evaluate the effects of cyclophosphamide and decapeptyl (analogues of GnRH) on histomorphometry and stereology o...
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BACKGROUND Tetracarpidium conophorum (Mull. Arg.) Hutch. & Dalz is one of the many medicinal plants used for ages in folklore as male fertility enhancers. The current study evaluates the effect of the plant leaf extract on alcohol - induced reproductive toxicity in male rats. METHODS Thirty rats were randomly divided into six groups of five animals each; Group 1 (positive control) received no...
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متن کاملRutin ameliorates methotrexate induced hepatic injury in rats.
PURPOSE To investigate the possible protective effect of rutin on methotrexate induced hepatotoxicity in rats. METHODS Twenty-two rats were divided into three experimental groups; Control-saline, Mtx, Mtx+Rutin. Hepatic tissue was taken for histological assessment and biochemical assays. Oxidative stress parameters malondialdehyde (MDA), glutathione peroxidase (GSH-Px) and superoxide dismutas...
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ژورنال
عنوان ژورنال: Toxicology International
سال: 2012
ISSN: 0971-6580
DOI: 10.4103/0971-6580.97224